Extremes of body composition may affect accuracy of estimation.


Creatinine Clearance (mL/min) = {(140 – Age) x Wt x F}/ (P Creat x 0.814)


M= 1 (males); F=0.85 (females)


Age in years


Plasma creatinine concentration in umol/L


Weight in kg

Plasma creatinine range is 10 - 1300 umol/l
Age range is 0-110 years
Weight range is 20-120 kg
M = 1 and F = 0.85
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Cockcroft and Gault Creatinine clearance (eCrCl)


Reference Interval: 90 - 150 mL/min (lower values expected in older subjects)